Hepatitis B virus infects about 200 million people worldwide yearly. The consequences of the infection range from mild, self‐limiting hepatitis with full recovery and immunity to chronic infection with liver disease of varying severity, including fulminant hepatitis and death. Alternatively, individuals may become healthy carriers of the virus and thus serve as a reservoir of infection. In addition, all chronic carriers of the virus are also at risk for development of primary hepatocellular carcinoma later in life. Efforts to combat this (...) disease on a global scale require an inexpensive vaccine. Studies of the hepatitis B viral coat protein (HBsAg) have permitted the development of two generations of vaccine to date, and detailed structural studies of its antigenic sites may eventually allow the development of a completely synthetic (and therefore inexpensive) vaccine in the future. (shrink)

It is appropriate to open an essay in honor of someone by commemorating that person. When I think of Dallas Willard I think of someone who has not been afraid to point to Jesus and spiritual commitment in an age when most people are committed to themselves. Dallas has been very clear in all of his writings that knowing Jesus is not a hobby, a business transaction one makes and forgets, nor an add-on to life; it is an entry into (...) a journey God is to direct in the context of the uniqueness of His person and the enablement of His rule and presence. The Father leads, Jesus mediates and exemplifies, and the Spirit enables. This commitment to Jesus is the goal of this article. It deals with unique claims about Jesus within the Second Temple Judaism of the first century, as well as looking at what religious life was like in the first century Greco-Roman world. Such background might seem distant in a journal on spiritual formation, but let me warn you that is not the case. To understand the world in which “decisions” for Jesus were made is to appreciate what it took to receive Jesus and begin the journey with Him. The study hopes to show that Willard's emphasis that genuine faith in Jesus is life-changing came with the first century territory. I proceed in three parts: the Jewish context, the Greco-Roman context, and then the application. (shrink)

Individual choice and freedom are repeatedly invoked in contemporary policy debates, including those with a focus on risk behaviors such as smoking and health insurance coverage. The idea of making the right choice with regard to health and well-being has been fortified by the neoliberal discourse of self-reliance, personal autonomy, and responsibility. This neoliberal view, stemming from the conceptualization of freedom of philosopher John Stuart Mill justifying the freedom of the individual in opposition to unlimited state control, holds that success, (...) good health, and favorable educational outcomes are largely due to individual effort. Correspondingly, so too is failure, including failure of.. (shrink)

Visual self-recognition is often controversially cited as an indicator of self-awareness and assessed with the mirror-mark test. Great apes and humans, unlike small apes and monkeys, have repeatedly passed mirror tests, suggesting that the underlying brain processes are homologous and evolved 14-18 million years ago. However, neuroscientific, developmental, and clinical dissociations show that the medium used for self-recognition (mirror vs photograph vs video) significantly alters behavioral and brain responses, likely due to perceptual differences among the different media and prior experience. (...) On the basis of this evidence and evolutionary considerations, we argue that the visual self-recognition skills evident in humans and great apes are a byproduct of a general capacity to collate representations, and need not index other aspects of self-awareness. (shrink)

The inconsistency between pro-environmental attitudes and behaviours, known as the “attitude-behaviour” gap, is exceptionally pronounced in scenarios associated with “green” choice. The current literature offers numerous explanations for the reasons behind the “attitude-behaviour” gap, however, the generalisability of these explanations is complex. In addition, the answer to the question of whether the gap occurs between attitudes and intentions, or intentions and behaviours is also unknown. In this study, we propose the moral dimension as a generalisable driver of the “attitude-behaviour” gap (...) and investigate its effectiveness in predicting attitudes, pro-environmental intentions and subsequent behaviours. We do so by using Hunt–Vitell’s moral philosophy-based framework of ethical decision-making, which conceptualises morality as the central decision-making parameter. The results from 557 US MTurk participants revealed that the manipulation of moral dimensions, specifically deontology and teleology, impacted ethical evaluation of presented dilemmas, however, failed to translate into subsequent intentions and behaviours. This finding suggests (i) that the moral dimension has an effect in shaping attitudes toward environmental issues, and (ii) that gap occurs between attitudes and intentions rather than intentions and behaviours. Further investigation of what strengthens and/or overrides the effects of the moral dimension would help understand the reasons why moral attitudes do not always translate into subsequent intentions and behaviours in the pro-environmental domain. (shrink)

The sixteen essays in Gender Struggles address a wide range of issues in gender struggles, from the more familiar ones that, for the last thirty years, have been the mainstay of feminist scholarship, such as motherhood, beauty, and sexual violence, to new topics inspired by post-industrialization and multiculturalism, such as the welfare state, cyberspace, hate speech, and queer politics, and finally to topics that traditionally have not been seen as appropriate subjects for philosophizing, such as adoption, care work, and the (...) home. (shrink)

This volume, modeled after those published in The Library of Living Philosophers, attempts to provide a coherent statement of the work of Abraham Edel in moral and political theory, and on the impact of his work on such diverse areas as education, law, and social science. The methodological element of Edel's work is to see ethical and social theory in the full context of human life; specifically how twentieth-century modes of analysis impact classical concerns about right and wrong, good and (...) evil. The volume is tightly integrated from start to finish, and has the benefit of Edel's thoughtful and thoroughgoing response to critics. In short, while this work is a tribute to the work of a scholar, it aims to serve as a basic guide through the labyrinthian world of contemporary ethical theory and social practice. Contents: Beryl Harold Levy, "Reflective Culture as Philosophy of Law"; Betty A. Sichel, "Abraham Edel's Contribution to Philosophy of Education"; Gerald E. Myers, "Person and Personality--and Respect for Both"; Mihailo Markovic, "Abraham Edel on the Method of Ethical Theory"; Helen Block Lewis, "Consequences for Ethical Theory of a Focus on the Psychology of Shame and Guilt"; Edmund L. Pincoffs, "Ethics as an Explanatory Undertaking"; Standish Thayer, "The Network of Concepts: A New View of Aristotle"; Mortimer R. Kadish, "Abraham Edel and the Dream of Science"; Michael Levin, "Reflections on Non-Cognitivism"; Ralph W. Sleeper, "Naturalizing Legal Positivism"; Irving Louis Horowitz, "The Political Philosophy of Abraham Edel"; Finbarr W. O'Connor, "Network Analysis in Ethics"; Elizabeth Flower, "A Moral Agenda for Ethical Theory"; Abraham Edel, "Responses to Critics"; "An Edel Bibliography.". (shrink)

L’écoute d’un couple en crise qui demande à être aidé montre fréquemment que la dégradation de leur communication affective et sexuelle a débuté à la naissance d’un enfant, pas nécessairement le premier. Quelques exemples témoignent à quel point de multiples remaniements psychiques s’opèrent au sein du couple, lorsqu’une femme devient mère : retour de l’enfant en soi, réactivation des conflits œdipiens. Et, comme le souligne Winnicott, n’y aurait-il pas en chaque homme et en chaque femme la représentation d’une femme/mère toute-puissante (...) et dominatrice, source d’angoisses multiples? Cette peur de la femme, qu’il faut donc à tout prix dominer, semble évidente lorsqu’on écoute les représentations que les adolescents se font de l’autre sexe. Les auteurs proposent quelques repères théoriques afin de comprendre ces angoisses et aider les couples à les reconnaître pour mieux les gérer. (shrink)

La demande en thérapie de couple revêt souvent la forme d’une plainte. Lorsque l’on s’attache à travailler les éléments conscients et inconscients qui structurent le transfert, on mesure à quel point cette plainte est séductrice. Elle exerce sur le thérapeute une emprise directe qui peut modifier son écoute et paralyser le processus thérapeutique, car elle a le pouvoir de s’introduire au cœur de son monde interne.

This volume addresses the intriguing issue of indirect reports from an interdisciplinary perspective. The contributors include philosophers, theoretical linguists, socio-pragmaticians, and cognitive scientists. The book is divided into four sections following the provenance of the authors. Combining the voices from leading and emerging authors in the field, it offers a detailed picture of indirect reports in the world’s languages and their significance for theoretical linguistics. Building on the previous book on indirect reports in this series, this volume adds an empirical (...) and cross-linguistic approach that covers an impressive range of languages, such as Cantonese, Japanese, Hebrew, Persian, Dutch, Spanish, Catalan, Armenian, Italian, English, Hungarian, German, Rumanian, and Basque. (shrink)

La supervision individuelle ou en groupe permet à tout thérapeute formé selon les concepts théoriques et l’approche clinique de la psychanalyse de forger ses propres outils. Dans un groupe de supervision, chacun apporte les difficultés sur lesquelles il bute dans la mise en place et le déroulement d’une thérapie. Le groupe réfléchit, dans tous les sens du terme, ce qui permet au thérapeute de percevoir ce qui jusque là lui échappait – qu’il s’agisse du fonctionnement symptomatique des patients entre eux (...) ou de ce qui se passe entre eux et lui lorsque s’éclairent les mouvements du transfert. Le groupe est à la fois environnement sécurisant, structure et appareil de liaison, la groupalité étant une dimension du sujet. Tout se passe comme si l’appareil psychique groupal reprenait à son compte le travail d’élaboration psychique du thérapeute, qui, pour le moment, se plaint de ne plus avoir la capacité de penser. Le superviseur est garant du cadre. De lui dépend également la spontanéité et la qualité des échanges ainsi que le climat de confiance indispensable au plaisir de travailler ensemble dans un rapport de parité. (shrink)

Cet ouvrage est construit autour d'un chapitre (texte original) de Judith Butler sur l'éthique de la non-violence. En réponse se construisent quatre réflexions philosophiques. Mylène Botbol-Baum présente le collectif à partir de sa traduction du texte de Judith Butler, et aborde la question du sujet et de la norme à partir de la lecture butlerienne de Levinas et Arendt, sur la question des limites de la légitimité de la violence pour une éthique de la relationalité. Jean de Munck (...) traite une lecture croisée de Benjamin et Butler sur la violence. Romildo Pineiro et Jose Erraruz off rent une lecture historique et politique du concept de violence et y confrontent l'interprétation de la non violence dans le texte de Butler. Trois textes plus sociologiques suivent sur l'impact de la non-violence, dans une perspective qui vise à " défaire le genre " dans le cadre sociopolitique critique des vulnérabilités, dans le cadre du travail des femmes migrantes (Ghaliya Dejelloul) ou du travail domestique non rémunéré (Anna Safuta), à partir d'une enquête sur la mobilité spatiale des femmes dans les zones pré-urbaines d'Alger ou de Bruxelles, off rant une analyse sur l'hostilité masculine et le rôle du discours religieux dans la légitimation de cette violence. Matthieu de Nanteuil conclut le volume sur la question de la violence et de la sensibilité politique en mettant à jour la théorie de la démocratie radicale chez Judith Butler. Il sera donc question dans ce volume de penser la non-violence à partir d'une approche fondée sur la normalisation des corps, en réintroduisant le sujet de la vie comme interlocuteur critique du sujet de la norme en démocratie. (shrink)

Comment départager ce qui est à travailler au sein du groupe thérapeutique et ce qui ne nous regarde pas, nous thérapeutes? Autant de frontières entre l’autre et soi, entre les motivations conscientes et les désirs inconscients, qui sont à la fois signifiantes et difficilement repérables. Le travail du thérapeute sur son contre-transfert lui permet de faire la différence entre ce qui ne le regarde pas et ce dont il préfère ne rien savoir.

À partir d’une situation de couple dans lequel la communication semble bloquée par un trop plein de souffrance, due en partie à des traumatismes dans les liens de filiation de part et d’autre, l’auteure, grâce à un groupe de recherche, expérimente la nécessité d’un nouvel espace pour réguler un transfert massif. Le groupe de recherche prend en quelque sorte le relais de l’appareil psychique du thérapeute et met en scène les émotions et les représentations qui sont à l’œuvre au sein (...) du groupe thérapeutique. Il devient un lieu de dépôt et de mentalisation des émotions qui circulent dans le transfert, et se fait le porte-voix des souffrances traumatiques enfermées dans les incorporats, ces ratés de l’introjection. (shrink)

This report describes the rationale, approaches, organization, and resource development leading to a large-scale deletion bin map of the hexaploid wheat genome. Accompanying reports in this issue detail results from chromosome bin-mapping of expressed sequence tags representing genes onto the seven homoeologous chromosome groups and a global analysis of the entire mapped wheat EST data set. Among the resources developed were the first extensive public wheat EST collection. Described are protocols for sequencing, sequence processing, EST nomenclature, and the assembly of (...) ESTs into contigs. These contigs plus singletons were used for selection of distinct sequence motif unigenes. Selected ESTs were rearrayed, validated by 5′ and 3′ sequencing, and amplified for probing a series of wheat aneuploid and deletion stocks. Images and data for all Southern hybridizations were deposited in databases and were used by the coordinators for each of the seven homoeologous chromosome groups to validate the mapping results. Results from this project have established the foundation for future developments in wheat genomics. (shrink)

What is it about you in virtue of which you are having the thoughts you are now having? The answer will no doubt make some appeal to the state your brain is now in. Most philosophers, however, claim that this is only part of the answer; many of the facts that determine your thoughts lie outside your skin. This view is called externalism, and in this book Keith L. Butler argues that, contrary to widespread philosophical opinion, externalism is very (...) implausible. Through critical evaluation of a vast amount of philosophical work on the subject, Butler shows that externalism faces problematic epistemological implications (regarding self-knowledge and knowledge of the external world), and problematic metaphysical implications (regarding mental causation). Moreover, externalism derives no support from an appeal to the cognitive sciences. The controversy generated by this book bears on issues in the philosophy of mind, language, science, and epistemology. It is required reading for serious students and professionals concerned with these areas of philosophy. (shrink)

RÉSUMÉ : Dans le Traité 1.4.4, Hume a présenté au nom des philosophes modernes un argument causal qui démontre que nos impressions des qualités secondaires ne ressemblent pas aux qualités des objets eux-mêmes. Les prédécesseurs de Hume n’ont pourtant pas employé d’argument causal, mais l’argument des qualités contraires. Je soutiens que la présentation qu’en a fait Hume n’est pas simplement à mettre au compte d’une différence stylistique «gratuite» mais est une correction importante dans la foulée de ses propres découvertes philosophiques.

Categories We Live By makes several claims about Judith Butler's Gender Trouble which Butler seeks to contest, while remaining in fundamental agreement with most of the conclusions in Asta Sveinsdottir's book. At issue is whether or not performativity can rightly be restricted to what is called an exercitive in J. L. Austin's sense, whether Butler is a radical constructivist or a qualified one, and whether unauthorized speech acts have a power to bring a reality into being that (...) is different from those authorized by legal regimes. Along the way, Butler suggest that establishing facts takes place within variable historical schemes and that this argument is neither a denial or facts nor of materiality. Finally, an individualist idea of freedom is subject to criticism in order to make way for an historically constrained freedom, collective in nature. (shrink)

Résumé Si l’espoir est une revendication impossible, alors nous exigeons l’impossible. Mais la vérité, c’est qu’il n’y a effectivement pas ici de revendications qui puissent être soumises à un arbitrage quelconque, parce que nous ne sommes pas réunis simplement pour exiger la justice économique et l’égalité sociale. Nous composons une communauté de corps ralliés dans les rues et dans les parcs.